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Can NAD+ Help You Bounce Back After Serious Illness? Here’s What the Science Says

Written by NAD Vitality Blend | Jun 17, 2025 8:22:08 PM

If you’ve recently battled a serious infection — pneumonia, sepsis, COVID-19, or anything that left you completely wiped out — you’re probably wondering how to rebuild your strength, energy, and immune system.

One word: NAD+.

What is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is a natural molecule found in every cell of your body. It fuels energy production, supports immune function, repairs DNA damage, and helps your body manage stress and inflammation.

The problem? Serious illness burns through NAD+ like wildfire.

During infections, your body enters high-alert mode: immune cells activate, inflammation surges, and your mitochondria (cellular power plants) work overtime. All of that rapidly depletes your NAD+ reserves — just when you need them most.


The Science: Can Replenishing NAD+ Help?

Animal studies say yes — and human data is catching up.

  • In pneumonia models, mice given NAD+ precursors (like nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN)) recovered faster, with less inflammation and better lung function (Zhang et al., Cell Reports, 2021).
  • In sepsis models, boosting NAD+ reduced mortality and organ damage (Hong et al., 2018).
  • Even in SARS-CoV-2 studies, NAD+ repletion helped reduce viral replication and supported immune resilience (Heer et al., 2020).

And while large human trials are still ongoing, small studies show promising benefits in patients recovering from COVID-19, chronic fatigue, and critical illness, including improved energy, reduced inflammation, and better cognitive function.

The Bottom Line

If you’re recovering from pneumonia, sepsis, or another serious illness, NAD+ may be the missing link in your recovery. It supports your energy, immune system, and repair processes — right when your body needs the boost.

Think of it as cellular rehab.

While NAD+ won’t replace antibiotics or medical care, it may speed your return to strength — and help you feel like yourself again.

Best way to increase NAD+?

NadVitalityBlend which helps your cells make more NAD and blocking enzymes that break down NAD!

 

Sources

  • Zhang, H. et al. Cell Reports, 2021. “NAD+ replenishment improves recovery in murine  pneumonia.”

  • Hong, S. et al. Frontiers in Immunology, 2018. “NAD+ augmentation reduces organ injury in sepsis.”

  • Heer, C. D. et al. Nature Communications, 2020. “NAD+ metabolism in SARS-CoV-2 infection.”

  • ClinicalTrials.gov: NAD+ in COVID-19 Recovery